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Chun-Yuh C. Huang

Photo of Chun-Yuh C. Huang

Chun-Yuh C. Huang

Associate Professor | College of Engineering | Biomedical Engineering Department
Work Phone: (305) 284-1320



Research Interests

Mechanobiology, Biomechanics, Stem cells, Tissue Engineering


    • Columbia University, Ph.D. in Mechanical Engineering/Biomechanics. (2001)
    • Columbia University, Other in Mechanical Engineering/ Biomechanics. (1998)
    • National Chiao Tung University, M.S. in Mechanical Engineering. (1993)
    • National Chiao Tung University, B.S. in Mechanical Engineering. (1991)


    • University of Miami, Associate Professor. Biomedical Engineering (2015 - Present)
    • Nova Southeastern University College of Dental Medicine, Adjunct Professor. (2009 - Present)
    • University of Miami, Assistant Professor (tenure-track). Biomedical Engineering (2009 - 2015)
    • Nova Southeastern University College of Dental Medicine, Assistant Professor. Pediatric Dentistry (2006 - 2008)
    • University of Miami, Research Assistant Professor. Biomedical Engineering (2006 - 2007)
    • University of Miami, Assistant Scientist. Biomedical Engineering (2005 - 2006)
    • Miami VA Medical Center, Postdoctoral Research Scientist . (2001 - 2005)
    • Columbia University College of Physicians and Surgeons, Graduate Research Assistant. Orthopaedic Surgery (1996 - 2001)
    • National Chiao Tung University, Graduate Research Assistant. Mechanical Engineering (1991 - 1993)


  • Juried or Refereed Journal Articles or Exhibitions

    • Genemaras, A., Ennis, H., Kaplan, L., Huang, C. (2016).Inflammatory Cytokines Induce Specific Time- and Concentration-Dependent MicroRNA Release by Chondrocytes, Synoviocytes and Meniscus Cells. Journal of Orthopaedic Research, in press.
    • Vernon, L., Vance, D., Wang, L., Rampersaud, E., Vance, J., Pericak-Vance, M., Huang, C., Kaplan, L. (2016).Regional Differential Genetic Response of Human Articular Cartilage to Impact Injury. Cartilage, in press.
    • Genemaras, A., Reiner, T., Huang, C., Kaplan, L. (2015).Early Intervention with Interleukin-1 Receptor Antagonist Protein Modulates Catabolic microRNA and mRNA Expression in Cartilage after Impact Injury. Osteoarthritis and Cartilage, 23, 2036-44.
    • Perez, J., Kaplan, L., Huang, C. (2015).Mechanical Injury of Knee Articular Cartilage in Sports-Related Exercise and Potential Post-Injury Preventative Therapy. Current Tissue Engineering, 4, 67-76.
    • Genemaras, A., Huang, C., Kaplan, L. (2015).MicroRNA Therapies for Osteoarthritis and its Symptoms. Current Tissue Engineering, 4, 86-94.
    • Gonzales, S., Wang, C., Levene, H., Cheung, H., Huang, C. (2014).ATP Promotes the Extracellular Matrix Biosynthesis of Intervertebral Disc Cells. Cell and Tissue Research, In press.
    • Gonzales, S., Rodriguez, B., Barrera, C., Huang, C. (2014).Measurement of ATP-Induced Transmembrane Potential Changes in IVD cells. Cellular and Molecular Bioengineering, 7, 598-606.
    • Mayo, V., Sawatari, Y., Huang, C., Garcia-Godoy, F. (2014).Neural Crest-Derived Dental Stem Cells - Where We Are and Where We Are Going. Journal of Dentistry, 42, 1043-51.
    • Vernon, L., Abadin, A., Wilensky, D., Huang, C., Kaplan, L. (2014).Sub-Physiological Mechanical Loading Reduces Apoptosis Following Acute Impact Injury in a Porcine Cartilage Model. Sports Health, 6, 81-8.
    • Wang, C., Gonzales, S., Levene, H., Gu, W., Huang, C. (2013).Energy Metabolism of Intervertebral Disc under Mechanical Loading. Journal of Orthopedic Research, 31, 1733-8.
    • Pelaez, D., Huang, C., Cheung, H. (2013).Isolation of Pluripotent Neural Crest Derived Stem Cells from Adult Human Tissues by Connexin 43 Enrichment. Stem Cells and Development, 22, 2906-14.
    • Kandalam, U., Bouvier, A., Casas, S., Smith, R., Gallego, A., Rothrock, J., Thompson, J., Huang, C., Stelnicki, E. (2013).Novel Bone Adhesives: A Comparison of Bond Strengths In Vitro. International Journal of Oral Maxillofacial Surgery, 42, 1054-9.
    • Wang, C., Huang, C., Lin, W. (2013).Optical ATP Biosensor for Extracellular ATP Measurement. Biosensors and Bioelectronics, 43, 355-361.
    • Jackson, A., Yuan, T., Huang, C., Brown, M., Gu, W. (2012).Nutrient Transport in Human Annulus Fibrosus is Affected by Compressive Strain and Anisotropy. Annals of Biomedical Engineering, 40, 2551-8.
    • Huang, C., Travascio, F., Gu, W. (2012).Quantitative Analysis of Exogenous IGF-1 Administration of Intervertebral Disc Through Intradiscal Injection. Journal of Biomechanics, 45, 1149-55.
    • Jackson, A., Huang, C., Brown, M., Gu, W. (2011).3D Finite Element Analysis of Nutrient Distributions and Cell Viability in the Intervertebral Disc: Effects of Deformation and Degeneration. Journal of Biomechanical Engineering, 133, 91006.
    • Salvatierra, J., Yuan, T., Fernando, H., Castillo, A., Gu, W., Cheung, H., Huang, C. (2011).Difference in Energy Metabolism of Annulus Fibrosus and Nucleus Pulposus Cells of The Intervertebral Disc,. Cellular and Molecular Bioengineering, 4, 302-310.
    • Jackson, A., Huang, C., Wu, W. (2011).Effect of Endplate Calcification and Mechanical Loading on the Distribution of Glucose in Intervertebral Disc: A 3-D Finite Element Study. Computer Methods in Biomechanics and Biomedical Engineering, 14, 195-204.
    • Fernando, H., Czamanski, J., Yuan, T., Gu, W., Huang, C. (2011).Mechanical Loading Affects the Energy Metabolism of Intervertebral Disc Cells. Journal of Orthopedic Research, 29, 1634-41.
    • Yuan, T., Huang, C., Gu, W. (2011).Novel Technique for Online Characterization of Cartilaginous Tissue Properties. Journal of Biomechanical Engineering, 133, 94504.
    • Yang, Z., Huang, C., Candiotti, K., Zeng, X., Yuan, T., Li, J., Yu, H., Abdi, S. (2011).Sox-9 Facilitates Differentiation of Adipose Tissue-Derived Stem Cells Into A Chondrocyte-like Phenotype In Vitro. Journal of Orthopedic Research, 29, 1291-7.
    • Chadipiralla, K., Yochim, J., Bahuleyan, B., Huang, C., Garcia-Godoy, F., Murray, P., Stelnicki, E. (2010).Osteogenic Differentiation of Stem Cells Derived From Human Periodontal Ligaments and Pulp of Human Exfoliated Deciduous Teeth. Cell and Tissue Research, 340, 323-33.
    • Jackson, A., Yuan, T., Huang, C., Gu, W. (2009).A Conductivity Approach to Measuring Fixed Charge Density in Intervertebral Disc Tissue. Annals of Biomedical Engineering, 12, 2566-2573.
    • Pelaez, D., Huang, C., Cheung, H. (2009).Dynamic Compression Maintains Viability and Induces Chondrogenesis of Human Mesenchymal Stem Cells in Fibrin Gel Scaffolds. Stem Cells and Development, 18, 93-102.
    • Flagler, D., Huang, C., Yuan, T., Cheung, H., Gu, W. (2009).Intracellular Flow Cytometric Measurement of Extracellular Matrix Components in Porcine Intervertebral Disc Cells. Cellular and Molecular Bioengineering, 2, 264-273.
    • Huang, C., Pelaez, D., Dominguez-Bendala, J., Garcia-Godoy, F., Cheung, H. S. (2009).Plasticity of Stem Cells Derived from Adult Periodontal Ligament. Regenerative Medicine, 4, 809-821.
    • Bahuleyan, B., Cheung, H., Huang, C. (2009).Role of Biomechanical Force in Stem Cell-based Therapy for Cartilage Repair. Current Rheumatology Review, 5, 34-39.
    • Yuan, T., Jackson, A., Huang, C., Gu, W. (2009).Strain-dependent Diffusion Coefficient of Oxygen in Bovine Annulus Fibrosus. Journal of Biomechanical Engineering, 131, 74503.
    • Huang, C., Wang, V., Flatow, E., Mow, V. (2009).Temperature-Dependent Viscoelastic Properties of the Human Supraspinatus Tendon. Journal of Biomechanics, 42, 546-549.
    • Jackson, A., Yuan, T., Huang, C., Travascio, F., Gu, W. (2008).Effect of Compression and Anisotropy on the Diffusion of Glucose in Annulus Fibrosus. Spine, 33, 7-Jan.
    • Huang, C., Gu, W. (2008).Effects of Mechanical Compression on Metabolism and Distribution of Oxygen and Lactate in Intervertebral Disc. Journal of Biomechanics, 41, 1184-1196.
    • Huang, C., Deitzer, M., Cheung, H. (2007).Effects of fibrinolytic Inhibitors on Chondrogenesis of Bone Marrow Mesenchymal Stem Cells in Fibrin Gels. Journal of Biomechanics and Modeling in Mechanobiology, 6, 11-May.
    • Huang, C., Yuan, T., Jackson, A., Hazbun, L., Fraker, C., Gu, W. (2007).Effects of Low Glucose Concentrations on Oxygen Consumption Rates of Intervertebral Disc Cells. Spine, 32, 2063-2069.
    • Huang, C., Gu, W. (2007).Effects of Tension-Compression Nonlinearity on Solute Transport in Charged Hydrated Fibrous Tissues under Dynamic Unconfined Compression. Journal of Biomechanical Engineering, 129, 423-429.
    • Huang, C., Stankiewicz, A., Ateshian, G., Mow, V. (2005).Anisotropy, Inhomogeneity, Tension-Compression Nonlinearity of Human Glenohumeral Cartilage in Finite Deformation. Journal of Biomechanics, 38, 799-809.
    • Huang, C., Pawluk, R., Wang, V., Bucchieri, J., Levine, W., Bigliani, L., Mow, V., Flatow, E. (2005).Inhomogeneous Mechanical Behavior of the Human Supraspinatus Tendon Under Uniaxial Loading. Journal of Orthopaedic Research, 23, 924-930.
    • Huang, C., Reuben, P., Cheung, H. (2005).Temporal Expression Patterns and Corresponding Protein Inductions of Early Responsive Genes in Rabbit Bone-Marrow Derived Mesenchymal Stem Cells Under Cyclic Compressive Loading. Stem Cells, 23, 1113-1121.
    • Huang, C., Reuben, M., D'Ippolito, G., Schiller, P., Cheung, H. (2004).Chondrogenesis of Human Bone Marrow Derived Mesenchymal Stem Cell in Agarose Culture. Anatomical Record, 278A, 428-436.
    • Huang, C., Hagar, C., Frost, L., Sun, Y., Cheung, H. (2004).Effects of Cyclic Compressive Loading on Chondrogenesis of Rabbit Bone-Marrow Derived Mesenchymal Stem Cells. Stem Cells, 22, 313-323.
    • Sun, Y., Firestein, G., Wenger, L., Huang, C., Cheung, H. (2004).Establishment of Immortal Fibroblast-like Synoviocyte Cell Line by Introduction of Human Telomerase. Biochemical and Biophysical Research Communications, 323, 1287-1292.
    • Huang, C., Soltz, M., Kopacz, M., Mow, V., Ateshian, G. (2003).Experimental Verification of the Role of Intrinsic Matrix Viscoelasticity and Tension-Compression Nonlinearity in the Biphasic Response of Cartilage in Unconfined Compression. Journal of Biomechanical Engineering, 125, 84-93.
    • Gu, W., Yao, H., Huang, C., Cheung, H. (2003).New Insight into Deformation-Dependent Hydraulic Permeabilty and Dynamic Compressive Behavior of Agarose Gels. Journal of Biomechanics, 36, 593-598.
    • Huang, C., Mow, V., Ateshian, G. (2001).The Role of Flow-Independent Viscoelasticity in the Biphasic Tensile and Compressive Responses of Articular Cartilage. Journal of Biomechanical Engineering, 123, 410-417.
    • Pollock, R., Wang, V., Bucchieri, J., Cohen, N., Huang, C., Pawluk, R., Flatow, E., Bigliani, L., Mow, V. (2000).Effects of Repetitive Subfailure Strains on the Mechanical Behavior of the Inferior Glenohumeral Ligament. Journal of Shoulder and Elbow Surgery, 70A, 1224-1230.
    • Yang, K., Huang, C. (1997).Collision-Free Path Planning and Modification Based On Task Requirements. Mechanism and Machine Theory, 32, 21-37.
  • Book Chapters

    • Vernon, L., Kaplan, L., Huang, C., (2012). Stem Cell Based Bone Tissue Engineering. Bone Regeneration -- Chapter: 1 (pp. Nov-32). InTech - Open Access Publisher.