Biologically Inspired Engineering: From Human Organs-on-Chips to Programmable Nanotherapeutics
Dr. Donald Ingber
Professor of Bioengineering, Harvard John. A. Paulson School of Engineering & Applied Sciences
The Wyss Institute for Biologically Inspired Engineering at Harvard University that I lead has pioneered a new model for innovation, trans-disciplinary collaboration and technology translation. I will highlight engineering of “Organs-on-Chips” that recapitulate organ-level structure and functions as a way to replace animal testing for drug development, mechanistic discovery, and personalized medicine; nanotherapeutics that target to vascular occlusion sites like artificial platelets; anticoagulant surface coatings for medicine devices inspired by a plant; a ‘biospleen’ device that cleanses blood of pathogens and toxins in septic patients; and self-assembling DNA-based nanorobots that can be programmed to travel to cancer sites and kill tumor cells. This new bioinspired technology wave represents a major paradigm shift in medicine, and the novel organizational structure of the Institute offers an entirely new way to translate discoveries into breakthrough products in the academic setting.
Live Broadcast: coe.miami.edu/speaker/ingber
Dr. Donald Ingber is the Founding Director of the Wyss Institute for Biologically Inspired Engineering at Harvard University the Judah Folkman Professor of Vascular Biology at Harvard Medical School & Boston Children’s Hospital, and Professor of Bioengineering, Harvard John. A. Paulson School of Engineering & Applied Sciences. He is a member of the National Academy of Medicine, National Academy of Inventors, American Institute for Medical and Biological Engineering, and American Academy of Arts and Sciences.